All patients examined in the inability to use tramodol celebrated psychic discomfort, depressed mood, a feeling of inner tension, anxiety, irritability, conflicts, aggressive behavior toward family members. The attraction to the drug usually bore obsessive nature (by J.H. Pyatnitskaya, 1975). When the systematic abuse of tramadol for three to four months, formed a typical withdrawal syndrome. Its main features are autonomic symptoms: sweating, chills, a feeling of “chills, bumps, mild tachycardia (heart rate to 90 per minute), tremor of the fingers, malaise, muscular discomfort, inability to find a comfortable position. There have been a sleep disorder. The duration of somato-autonomic disorders in a position to cancel ranged from 5 to 7 days. Most long-preserved emotional disturbances in the form of a sense of inner tension, anxiety, irritability, conflict.

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Systematic use of tramodol is accompanied by characteristic changes in behavior. Some of the examined patients admitted to stealing money from relatives and sale of items made from home to purchase tramodol, which is usually once was used for the purpose of intoxication. In other cases of this kind of behavior of patients became aware of the words of their relatives, who also noted a negative change in the nature of the patients. According to the observations of relatives, to the extent of dependence on Tramadol, patients become increasingly insensitive, rude and prone to lying. Thus, we can conclude that the use of tramadol there is typical of all drug regress personality known in the literature as Broytigam’s syndrome (W. Brautigam).

Should also note what is happening under the influence of the use of Tramodol sharpening premorbid psychological traits found in individuals predisposed to disease drug profiling..

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